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Publications

Publications from our faculty. In order to find a specific publication, use the search box below to search by author, title, journal or date.

April 14, 2025
PLOS Computational Biology
Revealing non-trivial information structures in aneural biological tissues via functional connectivity

Douglas Blackiston, Hannah Dromiack, Caitlin Grasso, Thomas F Varley, Douglas G Moore, Krishna Kannan Srinivasan, Olaf Sporns, Joshua Bongard, Michael Levin, Sara I Walker
April 16, 2025
Nature Communications
Dysregulation of N-terminal acetylation causes cardiac arrhythmia and cardiomyopathy

Daisuke Yoshinaga, Isabel Craven, Rui Feng, Maksymilian Prondzynski, Kevin Shani, Yashasvi Tharani, Joshua Mayourian, Milosh Joseph, David Walker, Raul H. Bortolin, Chrystalle Katte Carreon, Bridget Boss, Sheila Upton, Kevin Kit Parker, William T. Pu & Vassilios J. Bezzerides
April 8, 2025
Journal of the American Chemical Society
High-Throughput Extracellular Vesicle Isolation Using Plate-Based Size Exclusion Chromatography and Automation

Tal Gilboa, Dmitry Ter-Ovanesyan, Clarissa May Babila, Sara Whiteman, Shad Morton, David Kalish, Jamie Johnston, David Tesin, Matthew Davies, Jenny M. Tam, George M. Church, David R. Walt
April 9, 2025
Science Advances
Preference-based assistance optimization for lifting and lowering with a soft back exosuit

Philipp Arens, D Adam Quirk, Weiwei Pan, Yaniv Yacoby, Finale Doshi-Velez, Conor J Walsh
March 12, 2025
International Journal of Molecular Sciences
Host Serine Proteases and Antiviral Innate Immunity as Potential Therapeutic Targets in Influenza A Virus Infection-Induced COPD Exacerbations

Haiqing Bai, Melissa Rodas, Longlong Si, Yuncheng Man, Jie Ji, Roberto Plebani, Johnathan D Mercer, Rani K Powers, Chaitra Belgur, Amanda Jiang, Sean R R Hall, Rachelle Prantil-Baun, Donald E Ingber
March 26, 2025
ACS Applied Materials & Interfaces
Electrical Impedance Correlated to Flow Rate in Elastomeric Valves: An Analog Material Memory

Joel Dungan, Juanita Mathews, Jeffrey T. Borenstein, Michael Levin, Valencia Koomson
March 13, 2025
ACS Synthetic Biology
XanthoMoClo─A Robust Modular Cloning Genetic Toolkit for the Genera Xanthobacter and Roseixanthobacter

Maximillian P. M. Soltysiak, Audrey L. H. Ory, Andrew D. Lee, Caroline E. Christophersen, Amogh P. Jalihal, Michael Springer
March 17, 2025
Journal of Extracellular Vesicles
Toward Identification of Markers for Brain-Derived Extracellular Vesicles in Cerebrospinal Fluid: A Large-Scale, Unbiased Analysis Using Proximity Extension Assays

Maia Norman, Adnan Shami-shah, Sydney C. D'Amaddio, Benjamin G. Travis, Dmitry Ter-Ovanesyan, Tyler J. Dougan, David R. Walt
March 6, 2025
NPJ Precision Oncology
LINE-1 ORF1p expression occurs in clear cell ovarian carcinoma precursors and is a candidate blood biomarker

Pamela R. de Santiago, Sho Sato, Stephanie J. Zhang, Meaghan C. Dougher, Kyle M. Devins, Agnes J. Bilecz, Sagar Rayamajhi, Gabriel Mingo, Hannah S. Rendulich, Yi Feng, Connie Wu, Martin S. Taylor, Yelena Zhuravlev, Euihye Jung, Dalia K. Omran, Tian-Li Wang, Ie-Ming Shih, Lauren E. Schwartz, Sarah Kim, Mark A. Morgan, Janos L. Tanyi, Kathleen H. Burns, Ernst Lengyel, Carlos Parra-Herran, Andrew K. Godwin, David R. Walt & Ronny Drapkin
March 6, 2025
biosensors
An Antimicrobial and Antifibrotic Coating for Implantable Biosensors

Sofia Wareham-Mathiassen, Pawan Jolly, Nandhinee Radha Shanmuga, Badrinath Jagannath, Pranav Prabhala, Yunhao Zhai, Alican Ozkan, Arash Naziripour, Rohini Singh, Henrik Bengtsson,Thomas Bjarnsholt, and Donald E. Ingber
February 24, 2025
Nature Protocols
Circular Vectors as an efficient, fully synthetic, cell-free approach for preparing small circular DNA as a plasmid substitute for guide RNA expression in CRISPR–Cas9 genome editing

Roman Teo Oliynyk & George M. Church
March 3, 2025
PNAS
Vimentin undergoes liquid-liquid phase separation to form droplets which wet and stabilize actin fibers

Arkaprabha Basu, Tommy Krug, Benjamin du Pont, Qiaoling Huang, Sijie Sun, Stephen A Adam, Robert D Goldman, David A Weitz
February 17, 2025
Communicative & Integrative Biology
Life, its origin, and its distribution: a perspective from the Conway-Kochen Theorem and the Free Energy Principle

Chris Fields, Michael Levin
February 1, 2025
Review of Scientific Instruments
A microfluidic sucrose gap device for electrical measurement of gap junction connectivity

J Dungan, J Mathews, M Levin, V Koomson
January 31, 2025
Science
Randomizing the human genome by engineering recombination between repeat elements

Jonas Koeppel, Raphael Ferreira, Thomas Vanderstichele, Lisa Maria Riedmayr, Elin Madli Peets, Gareth Girling, Juliane Weller, Pierre Murat, Fabio Giuseppe Liberante, Tom Ellis, George McDonald Church, Leopold Parts
January 31, 2025
Journal of Control Release
Immobilization of BMP-2 in porous hydrogels to spatially regulate osteogenesis

Junzhe Lou, Charlotte Meyer, Anqi Chen, David A Weitz, David J Mooney
February 1, 2025
SLAS Discovery
Comparative evaluation of cell-based assay technologies for scoring drug-induced condensation of SARS-CoV-2 nucleocapsid protein

Rui Tong Quek, Cyna R Shirazinejad, Christina L Young, Kierra S Hardy, Samuel Lim, Phillip J Elms, David T McSwiggen, Timothy J Mitchison, Pamela A Silver
January 29, 2025
Nature Portfolio Journal Women's Health
Cervical mucus in linked human Cervix and Vagina Chips modulates vaginal dysbiosis

Ola Gutzeit, Aakanksha Gulati, Zohreh Izadifar, Anna Stejskalova, Hassan Rhbiny, Justin Cotton, Bogdan Budnik, Sanjid Shahriar, Girija Goyal, Abidemi Junaid, Donald E Ingber
February 5, 2025
Lab on a Chip
TapeTech microfluidic connectors: adhesive tape-enabled solution for organ-on-a-chip system integration

Terry Chin, Abraham C I van Steen, Delaney Gray-Scherr, Jessica L Teo, Anish Vasan, Joshua Jeon, Jessica Shah, Aayush Pate, Amy E Stoddard, Jennifer L Bays, Jeroen Eyckmans, Christopher S Chen
January 23, 2025
EMBO Reports
Rapid human oogonia-like cell specification via transcription factor-directed differentiation

Merrick Pierson Smela, Christian C Kramme, Patrick R J Fortuna, Bennett Wolf, Shrey Goel, Jessica Adams, Carl Ma, Sergiy Velychko, Ursula Widocki, Venkata Srikar Kavirayuni, Tianlai Chen, Sophia Vincoff, Edward Dong, Richie E Kohman, Mutsumi Kobayashi, Toshi Shioda, George M Church, Pranam Chatterjee